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Cayman LY266097 (hydrochloride)
List Price
$55.00
Your Price
$55.00
Cayman LY266097 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-11935-1
MFG.PART:
11935-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LY266097 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT2B (Ki = 0.5 nM). It is selective for 5-HT2B over 5-HT2A and 5-HT2C receptors (Kis = 19.5 and 24.55 nM, respectively). LY266097 (100 nmol, intrathecal) reduces hind paw tactile allodynia induced by L5/L6 spinal nerve ligation in a rat model of neuropathic pain. It also reduces hyperlocomotion induced by cocaine in rats when administered at a dose of 0.63 mg/kg without reducing cocaine-induced dopamine outflow in the nucleus accumbens shell.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(2-chloro- 3,4-dimethoxy phenyl) methyl]- 2,3,4,9- tetrahydro-6- methyl-1H- pyrido[3,4-b] indole, monohydro chloride
CAS Number
172895-39-5
Molecular Formula
C21H23ClN2O2 • HCl
Formula Weight
407.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Chloroform: 30mg/mL
λmax
211, 228, 231, 242, 275 nm
SMILES
ClC1=C(OC)C(OC)=CC=C1CC(NCC2)C3=C2C4=CC(C)=CC=C4N3.Cl
InChi Code
InChI=1S/C21H23ClN2O2.ClH/c1-12-4-6-16-15(10-12)14-8-9-23-17(20(14)24-16)11-13-5-7-18(25-2)21(26-3)19(13)22;/h4-7,10,17,23-24H,8-9,11H2,1-3H3;1H
InChi Key
KPXKZZURYAXZQE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11935-1 |
|---|---|
| Supplier Part Number | 11935-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 172895-39-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |