We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Dapivirine
List Price
$49.00
Your Price
$49.00
Cayman Dapivirine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16247-1
MFG.PART:
16247-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No. ), inhibits HIV-1 reverse transcriptase with an IC50 value of 24 nM in vitro. It impedes the late stages of HIV-1 infection by interfering with HIV-1 Gag-Pol polyprotein processing.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
244767-67-7
Synonyms
- R147681
- TMC120
Molecular Formula
C20H19N5
Formula Weight
329.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 0.3 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 0.2 mg/mL
λmax
253, 283, 311 nm
SMILES
N#CC1=CC=C(NC2=NC=CC(NC3=C(C)C=C(C)C=C3C)=N2)C=C1
InChi Code
InChI=1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25)
InChi Key
ILAYIAGXTHKHNT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16247-1 |
|---|---|
| Supplier Part Number | 16247-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 244767-67-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |