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Cayman MDL 29951
List Price
$107.00
Your Price
$107.00
Cayman MDL 29951 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16266-1
MFG.PART:
16266-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NMDA receptors are neuroreceptors that have binding sites for glycine or D-serine as well as L-glutamate. MDL 29951 is an antagonist of NMDA receptors with high affinity for the glycine binding site (Ki = 140 nM). It is functional both in vitro and in vivo. MDL 29951 blocks NMDA receptor-dependent convulsions in audiogenic seizure-susceptible DBA/2J mice. It is used to evaluate the role of the glycine site of the NMDA receptor in neurological signaling., MDL 29951 is also an agonist of the g protein-coupled receptor GPR17 (EC50 values range from 7 nM to 6 µM, depending on the assay). GPR17 is thought to be involved in oligodendrocyte differentiation and myelin formation/repair.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-carboxy-4,6-dichloro-1H-indole-3-propanoic acid
CAS Number
130798-51-5
Molecular Formula
C12H9Cl2NO4
Formula Weight
302.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/mL
- DMSO: 10 mg/mL
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
- Ethanol: 0.25 mg/mL
λmax
309 nm
SMILES
ClC1=CC(Cl)=C(C(CCC(O)=O)=C(C(O)=O)N2)C2=C1
InChi Code
InChI=1S/C12H9Cl2NO4/c13-5-3-7(14)10-6(1-2-9(16)17)11(12(18)19)15-8(10)4-5/h3-4,15H,1-2H2,(H,16,17)(H,18,19)
InChi Key
KNBSYZNKEAWABY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16266-1 |
|---|---|
| Supplier Part Number | 16266-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 130798-51-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |