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Cayman Tenofovir Disoproxil (fumarate)
List Price
$297.00
Your Price
$297.00
Cayman Tenofovir Disoproxil (fumarate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16922-50
MFG.PART:
16922-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Tenofovir disoproxil is a prodrug of the acyclic nucleoside phosphonate, tenofovir (Item No. 13874).1,2 Tenofovir is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase.3,4 Due to its rapid intracellular uptake, the anti-HIV activity of tenofovir disoproxil is reportedly >100-fold greater than that of the negatively charged tenofovir in a T cell line and primary blood lymphocytes.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(5-[[(1R)-2-
CAS Number
202138-50-9
Synonyms
- Bis(POC)-PMPA
Molecular Formula
C19H30N5O10P • C4H4O4
Formula Weight
635.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 16 mg/mL
- DMF:PBS (pH 7.2) (1:9): 0.1 mg/mL
- DMSO: 14 mg/mL
- Ethanol: 5 mg/mL
λmax
209, 260 nm
SMILES
O=P(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)CO[C@H](C)CN1C=NC2=C(N)N=CN=C21.O=C(O)/C=C/C(O)=O
InChi Code
InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1
InChi Key
VCMJCVGFSROFHV-WZGZYPNHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16922-50 |
|---|---|
| Supplier Part Number | 16922-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 202138-50-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |