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Cayman Cariporide
List Price
$918.00
Your Price
$918.00
Cayman Cariporide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-16935-100
MFG.PART:
16935-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cariporide is an inhibitor of sodium-hydrogen exchanger 1 (NHE-1; IC50 = 0.56 µM in an intracellular pH recovery assay).1 It is selective for NHE-1 over NHE-2 (IC50 = 28 µM in an intracellular pH recovery assay). Cariporide inhibits sodium propionate-induced swelling of isolated human platelets (IC50 = 0.023 µM). It reduces the myocardial infarct size as a percentage of the area at risk in a rabbit model of ischemia-reperfusion injury induced by coronary artery occlusion when administered at a dose of 1 mg/kg. Cariporide (1 mg/kg) decreases ventricular tachycardia duration in a rat model of coronary artery ligation and reperfusion-induced arrhythmia.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
159138-80-4
Synonyms
- HOE 642
Molecular Formula
C12H17N3O3S
Formula Weight
283.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 20 mg/mL
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
- Ethanol: 10 mg/mL
λmax
210, 260 nm
SMILES
CS(C1=C(C(C)C)C=CC(C(NC(N)=N)=O)=C1)(=O)=O
InChi Code
InChI=1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)
InChi Key
IWXNYAIICFKCTM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16935-100 |
|---|---|
| Supplier Part Number | 16935-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 159138-80-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |