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Cayman SB-224289 (hydrochloride)
List Price
$110.00
Your Price
$110.00
Cayman SB-224289 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17036-10
MFG.PART:
17036-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine; 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-224289 is a potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold selectivity for human 5-HT1B over all other 5-HT receptors. It has been used to study the role of 5-HT1B receptors in cocaine self-administration and cocaine-seeking behavior.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1-biphenyl]-4-yl](2,5,6,7-tetrahydro-1-methylspiro[3H-furo[2,3-f]indole-3,4-piperidin]-5-yl)-methanone, monohydrochloride
CAS Number
180084-26-8
Molecular Formula
C32H32N4O3 • HCl
Formula Weight
557.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 5 mg/mL*
λmax
270 nm
SMILES
CN(CC1)CCC21COC3=C2C=C(N(C(C4=CC=C(C5=CC=C(C6=NOC(C)=N6)C=C5C)C=C4)=O)CC7)C7=C3
InChi Code
InChI=1S/C32H32N4O3/c1-20-16-25(30-33-21(2)39-34-30)8-9-26(20)22-4-6-23(7-5-22)31(37)36-13-10-24-17-29-27(18-28(24)36)32(19-38-29)11-14-35(3)15-12-32/h4-9,16-18H,10-15,19H2,1-3H3
InChi Key
ATQMRMGXINTJHV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17036-10 |
|---|---|
| Supplier Part Number | 17036-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 180084-26-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |