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Cayman Vlx600; Purity- Greater Than Or Equal To 95%; Size- 1 Mg;
List Price
$37.00
Your Price
$37.00
Cayman Vlx600; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17192-1
MFG.PART:
17192-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
VLX600 is a compound that shows selective cytotoxicity against quiescent cancer cells (IC50 = 1-10 µM) with selectivity for malignant cells. It induces necrosis in non-proliferating quiescent core cells in multicellular spheroids (MCs) formed from HCT116 colon cancer cells. VLX600 induces the expression of genes associated with hypoxia, glycolysis, and p53 signaling, stimulates autophagy, and triggers mitochondrial dysfunction in MCs. It displays antitumor activity against colon cancer xenografts with minimal systemic toxicity in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(2-pyridinyl)-ethanone, 2-(6-methyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)hydrazone
CAS Number
327031-55-0
Molecular Formula
C17H15N7
Formula Weight
317.4
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 1 mg/ml
λmax
224, 262, 312, 370 nm
SMILES
C/C(C1=NC=CC=C1)=N/NC2=NC3=C(C(C=CC=C4C)=C4N3)N=N2
InChi Code
InChI=1S/C17H15N7/c1-10-6-5-7-12-14(10)19-16-15(12)22-24-17(20-16)23-21-11(2)13-8-3-4-9-18-13/h3-9H,1-2H3,(H2,19,20,23,24)/b21-11-
InChi Key
UQOSBPRTQFFUOA-NHDPSOOVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17192-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 17192-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 327031-55-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |