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Cayman Rs 504393; Purity- Greater Than Or Equal To 98%; Size- 10
List Price
$198.00
Your Price
$198.00
Cayman Rs 504393; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17330-10
MFG.PART:
17330-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes. It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.,, Cepharanthine can decrease LPS-stimulated expression of TNF-α, IL-6, and IL-1β in macrophages and prevent the activation of NF-κB, ERK, JNK, and p38 MAPK. It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3,13,14,14aS,15,26,26aR- octahydro- 22,30- dimethoxy- 1,14- dimethyl- 1H- 4,6:16,19- dietheno- 21,25- metheno- 12H- [1,3]dioxolo[4,5- g]pyrido[2’,3’:17,18][1,10]dioxacycloeicosino[2,3,4- ij]isoquinoline
CAS Number
481-49-2
Synonyms
- O-Methylcepharanoline
- NSC 623442
Molecular Formula
C37H38N2O6
Formula Weight
606.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 2 mg/ml
λmax
283 nm
SMILES
CN1CCC(C=C(OCO2)C2=C3OC4=C(OC)C=C(CCN(C)[C@]5([H])CC6=CC=C(OC)C7=C6)C5=C4)=C3[C@]1([H])CC8=CC=C(O7)C=C8
InChi Code
InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1
InChi Key
YVPXVXANRNDGTA-WDYNHAJCSA-N
Origin
Plant/Stephania japonica
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17330-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 17330-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 300816-15-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |