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Cayman Verteporfin
List Price
$32.00
Your Price
$32.00
Cayman Verteporfin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17334-1
MFG.PART:
17334-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces a highly reactive short-lived singlet oxygen and other reactive oxygen radicals, generating local damage to the endothelium and vessel occlusion. Verteporfin can also inhibit autophagosome formation by directly targeting and modifying p62, a scaffold and adaptor protein that binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid, monomethyl ester
CAS Number
129497-78-5
Synonyms
- BPD-MA
- CL 318,952
Molecular Formula
C41H42N4O8
Formula Weight
718.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/mL
- DMF:PBS (pH 7.2); (1:7): 0.1 mg/mL
- DMSO: 50 mg/mL
λmax
214, 345, 435, 566, 682 nm
SMILES
CC1=C(CCC(O)=O)/C([N]=C1/C=C(C(C=C)=C/2C)\[NH]C2=C/3)=C/C4=C(CCC(OC)=O)C(C)=C(/C=C5[N]=C3C6=CC=C(C(OC)=O)[C@@H](C(OC)=O)[C@@]\56C)[NH]4
InChi Code
InChI=1S/C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)25(12-15-37(48)51-6)33(44-30)18-32-24(11-14-36(46)47)21(3)28(43-32)16-31(23)42-29/h9-10,13,16-19,38,42,44H,1,11-12,14-15H2,2-8H3,(H,46,47)/b28-
InChi Key
YTZALCGQUPRCGW-MXVXOLGGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17334-1 |
|---|---|
| Supplier Part Number | 17334-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 129497-78-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |