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Cayman ZSTK474
List Price
$85.00
Your Price
$85.00
Cayman ZSTK474 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17381-10
MFG.PART:
17381-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ZSTK474 is a triazine derivative that acts as an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms (IC50s = 17, 53, and 6 nM for p110β, -γ, and -δ, respectively). It is selective for PI3K, as it has negligible activity against 139 other kinases when tested at 30 µM. ZSTK474 is orally bioavailable and shows strong antitumor activity against human cancer xenografts in mice. The efficacy of ZSTK474 against certain cancer cells and tumors can be enhanced by combination therapy.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(difluoromethyl)-1-
CAS Number
475110-96-4
Molecular Formula
C19H21F2N7O2
Formula Weight
417.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMSO: 20 mg/mL
λmax
240 nm
SMILES
FC(F)C1=NC(C=CC=C2)=C2N1C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3
InChi Code
InChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
InChi Key
HGVNLRPZOWWDKD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17381-10 |
|---|---|
| Supplier Part Number | 17381-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 475110-96-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |