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Cayman Felodipine
List Price
$110.00
Your Price
$110.00
Cayman Felodipine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17535-25
MFG.PART:
17535-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Felodipine is an inhibitor of L-type calcium channels.1 It induces relaxation of precontracted isolated porcine coronary artery segments (EC50 = 0.15 nM), which highly express L-type calcium channels.2 Felodipine is selective for L-type calcium channels over N-, R-, and P/Q-type channels at 10 µM, as well as the T-type Cav3.2 channel (IC50 = 6.8 µM).1,3 Felodipine preferentially inhibits L-type calcium channels in isolated rat portal vein over rat left ventricle (IC50s = 33.9 and 3,981 nM, respectively).4 It decreases mean arterial blood pressure and total peripheral resistance in a rabbit model of hypertension induced by renal artery ligation when administered intravenously at doses of 30 and 100 nmol/kg.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(2,3-dichloro
CAS Number
72509-76-3
Synonyms
- H 154/82
Molecular Formula
C18H19Cl2NO4
Formula Weight
384.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/mL
- Ethanol: 20 mg/mL
λmax
236, 360 nm
SMILES
CC1=C(C(C(C(OCC)=O)=C(N1)C)C2=C(C(Cl)=CC=C2)Cl)C(OC)=O
InChi Code
InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
InChi Key
RZTAMFZIAATZDJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17535-25 |
|---|---|
| Supplier Part Number | 17535-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 72509-76-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |