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Cayman Pyridostatin; Purity- Greater Than Or Equal To 95%; Size-
List Price
$494.00
Your Price
$494.00
Cayman Pyridostatin; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18013-25
MFG.PART:
18013-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Pyridostatin is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres. It can compete for binding with the telomere-associated proteins and induce telomerase dysfunction. Pyridostatin induces DNA damage and cell cycle arrest (Kd = 490 nM) and has been shown to target the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(2-aminoeth oxy)-N2,N6- bis[4-(2- aminoethoxy)- 2-quinolinyl] -2,6-pyridine dicarboxamide, trifluoro acetate salt
CAS Number
1472611-44-1
Molecular Formula
C31H32N8O5 • C2HF3O2
Formula Weight
710.7
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 5 mg/ml
- PBS (pH 7.2): 5 mg/ml
λmax
228, 269, 311, 324 nm
SMILES
NCCOC1=CC(NC(C2=NC(C(NC3=CC(OCCN)=C(C=CC=C4)C4=N3)=O)=CC(OCCN)=C2)=O)=NC5=C1C=CC=C5.C#C(F)(F)F.O=O
InChi Code
InChI=1S/C31H32N8O5.C2HF3.O2/c32-9-12-42-19-15-24(30(40)38-28-17-26(43-13-10-33)20-5-1-3-7-22(20)36-28)35-25(16-19)31(41)39-29-18-27(44-14-11-34)21-6-2-4-8-23(21)37-29;1-2(3,4)5;1-2/h1-8,15-18H,9-14,32-34H2,(H,36,38,40)(H,37,39,41);1H;
InChi Key
AOHXRDMGALEMBB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18013-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 18013-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1472611-44-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |