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Cayman Dipyridamole; Purity- Greater Than Or Equal To 98%; Size-
Product Description
Dipyridamole is a phosphodiesterase 5A (PDE5A) inhibitor (IC50 = 574 nM) that prevents platelet aggregation by increasing cGMP levels and blocking the reuptake of adenosine via red blood cells., It also scavenges the free radicals that inactivate cyclooxygenase, leading to the inhibition of platelet activation and thrombin generation. Dipyridamole has also been shown to inhibit PDE11A with an IC50 value of 370 nM and equilibrative nucleoside transporter 1 (ENT1) with a Ki value of 8.18 nM., It inhibits replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero E6 cells when used at a concentration of 100 nM. Formulations containing dipyridamole in combination with aspirin (Item No. ) have been used to prevent stroke and other cardiovascular events.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 515776
- NSC 619103
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
- Ethanol: 5 mg/ml
Shipping & Storage Information
| SKU | CAYM-18189-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 18189-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 58-32-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |