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Cayman Cct128930; Purity- Greater Than Or Equal To 95%; Size- 1 M
List Price
$25.00
Your Price
$25.00
Cayman Cct128930; Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18194-1
MFG.PART:
18194-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CCT128930 is an ATP-competitive inhibitor of Akt2 (IC50 = 6 nM). It is selective for Akt over a panel of 47 other kinases, including the related protein kinase A and p70S6K. CCT128930 blocks the phosphorylation of Akt targets, inhibits proliferation of multiple tumor cell lines in vitro, and prevents the growth of human tumor xenografts in mice. CCT128930 has been used to elucidate the role of Akt2 in regulating the function of interacting proteins, modulating DNA damage and autophagy in HepG2 hepatoma cells, and cell survival and vasculogenesis in endothelial colony forming cells.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(4-chlorophenyl)
CAS Number
885499-61-6
Molecular Formula
C18H20ClN5
Formula Weight
341.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/ml
- DMSO: 5 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
220, 286 nm
SMILES
ClC(C=C1)=CC=C1CC(CC2)(N)CCN2C3=C4C(NC=C4)=NC=N3
InChi Code
InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23)
InChi Key
RZIDZIGAXXNODG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18194-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 18194-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 885499-61-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |