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Cayman Zileuton-d4
List Price
$253.00
Your Price
$253.00
Cayman Zileuton-d4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-26761-1
MFG.PART:
26761-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Zileuton-d4 is intended for use as an internal standard for the quantification of zileuton (Item No. ) by GC- or LC-MS. Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor. It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4; Item No. ) production induced by the calcium ionophore A23187 (Item No. ) in purified human peripheral blood polymorphonuclear leukocytes (PMNLs; IC50 = 0.6 µM). Zileuton (10 mg/kg, p.o.) prevents antigen challenge-induced increases in specific lung resistance in a sheep model of asthma at 4 to 8 hours post-challenge following administration 2 hours pre-challenge. Formulations containing zileuton have been used in the prophylaxis and chronic treatment of asthma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(1-benzo
CAS Number
1189878-76-9
Molecular Formula
C11H8D4N2O2S
Formula Weight
240.3
Purity
≥99% deuterated forms (d1-d4)
Formulation
A solid
Solubility
- DMSO: slightly soluble
- Methanol: very slightly soluble
SMILES
ON(C(N)=O)C(C([2H])([2H])[2H])([2H])C1=CC2=CC=CC=C2S1
InChi Code
InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)/i1D3,7D
InChi Key
MWLSOWXNZPKENC-CWIRFKENSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26761-1 |
|---|---|
| Supplier Part Number | 26761-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1189878-76-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |