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Cayman H-Val-Pro-Pro-OH (trifluoroactetate salt)
List Price
$49.00
Your Price
$49.00
Cayman H-Val-Pro-Pro-OH (trifluoroactetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-28898-5
MFG.PART:
28898-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
H-Val-Pro-Pro-OH (VPP) is a peptide inhibitor of angiotensin-converting enzyme (ACE; IC50 = 9 µM). It inhibits acetylcholine-induced nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 1 µM and induces vasorelaxation in precontracted isolated rat aortic rings. VPP (0.3 mg/kg) decreases systolic blood pressure in spontaneously hypertensive, but not normotensive, rats. Dietary administration of VPP reduces plasma levels of total cholesterol, HDL-cholesterol, and triglycerides, expression of Il6 and Il1b, and aortic arch intimal thickening and atherosclerotic plaque formation in ApoE-/- mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-valyl-L-
Synonyms
- VPP
Molecular Formula
C15H25N3O4 • XCF3COOH
Formula Weight
311.4
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 15 mg/mL
- DMSO: 15 mg/mL
- Ethanol: 15 mg/mL
- PBS (pH 7.2): 10 mg/mL
SMILES
CC(C)[C@H](N)C(N1CCC[C@H]1C(N2CCC[C@H]2C(O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C15H25N3O4.C2HF3O2/c1-9(2)12(16)14(20)17-7-3-5-10(17)13(19)18-8-4-6-11(18)15(21)22;3-2(4,5)1(6)7/h9-12H,3-8,16H2,1-2H3,(H,21,22);(H,6,7)/t10-,11-,12-;/m0./s1
InChi Key
DJQRQUZDHQFFTH-LFELFHSZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-28898-5 |
|---|---|
| Supplier Part Number | 28898-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |