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Cayman Leoidin
List Price
$174.00
Your Price
$174.00
Cayman Leoidin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-29939-1
MFG.PART:
29939-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.,, It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S. pneumoniae (MICs = 8, 32, 1, 128, and 64 µg/mL, respectively). Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) isolated from P. aeruginosa (IC50 = 42 µM). It also inhibits organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 with Ki values of 0.08 and 1.84 µM, respectively, in CHO Cells expressing the human transporters.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,4-dichloro- 3,8-dihydroxy- 1,6,9-trimethyl- 11-oxo-11H- dibenzo[b,e] [1,4]dioxepin- 7-carboxylic acid, methyl ester
CAS Number
105350-54-7
Molecular Formula
C18H14Cl2O7
Formula Weight
413.2
Purity
≥95%
Formulation
A solid
Solubility
- DMF: soluble
- DMSO: soluble
- Ethanol: soluble
- Methanol: soluble
SMILES
CC1=C(O)C(C(OC)=O)=C(C)C2=C1OC(C3=C(C(Cl)=C(O)C(Cl)=C3C)O2)=O
InChi Code
InChI=1S/C18H14Cl2O7/c1-5-9-16(11(20)13(22)10(5)19)26-14-6(2)8(17(23)25-4)12(21)7(3)15(14)27-18(9)24/h21-22H,1-4H3
InChi Key
RCLFRVZNHRFQGE-UHFFFAOYSA-N
Origin
Fungus/Lecanora sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-29939-1 |
|---|---|
| Supplier Part Number | 29939-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 105350-54-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |