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Cayman (±)15-HEPE
List Price
$234.00
Your Price
$234.00
Cayman (±)15-HEPE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-32700-100
MFG.PART:
32700-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE (Item No. ). 15(S)-HEPE is formed from EPA via a 15(S)-HpEPE (Item No. ) intermediate, which is produced by 15-lipoxygenase (15-LO) and reduced by glutathione peroxidase (GPX)., (±)15-HEPE is active against P. acnes and S. aureus (MICs = 128 and 512 mg/L, respectively). It inhibits aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP (IC50 = 4.7 µM). Bronchoalveolar lavage fluid (BALF) levels of (±)15-HEPE are increased in patients with allergic asthma or COVID-19.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
15-hydroxy- 5Z,8Z,11Z,13E, 17Z-eicosa pentaenoic acid
CAS Number
88852-33-9
Synonyms
- (±)15-hydroxy Eicosapentaenoic Acid
- (±)15-hydroxy EPA
Molecular Formula
C20H30O3
Formula Weight
318.5
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- 0.1 M Na2CO3: 2 mg/mL
- DMF: Miscible
- DMSO: Miscible
- Ethanol: Miscible
- PBS pH 7.2: 0.8 mg/mL
λmax
236 nm
SMILES
CC/C=C\CC(O)\C=C\C=C\C/C=C\C/C=C\CCCC(=O)O
InChi Code
InChI=1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h3-5,8-11,13-14,17,19,21H,2,6-7,12,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,13-3-,17-14+
InChi Key
WLKCSMCLEKGITB-XWJJKCKWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-32700-100 |
|---|---|
| Supplier Part Number | 32700-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 88852-33-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |