Cell Signaling Hsp60 (D6f1) Xp ® Rabbit mAb (BSA And Azide Free)

Name: Cell Signaling Hsp60 (D6f1) Xp ® Rabbit mAb (BSA And Azide Free)
SKU: CSIG-56658SF
Price: 873.65 USD

List Price $873.65 Your Price $873.65

Cell Signaling Hsp60 (D6f1) Xp ® Rabbit mAb (BSA And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-56658SF

MFG.PART: 56658SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R Hm Mk X Z B Pg
Sensitivity	Endogenous
Molecular Weight (kDa)	60
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #12165
Specificity/Sensitivity	HSP60 (D6F1) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total HSP60 protein.
Species Reactivity	Human, Mouse, Rat, Hamster, Monkey, Xenopus, Zebrafish, Bovine, Pig
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Trp68 of human HSP60 protein.
Background	In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones (1-3). HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria (4). Research studies have shown that a significant amount of HSP60 is also present in the cytosol of many cells, and that it is induced by stress, inflammatory and immune responses, and autoantibodies correlated with Alzheimers, coronary artery diseases, MS, and diabetes (5-8).

Specifications