Cell Signaling Map4k3 (E9l1j) Rabbit mAb

Name: Cell Signaling Map4k3 (E9l1j) Rabbit mAb
SKU: CSIG-69387S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Map4k3 (E9l1j) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-69387S

MFG.PART: 69387S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	101
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:200}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	MAP4K3 (E9L1J) Rabbit mAb recognizes endogenous levels of total MAP4K3 protein. A band of unknown identity is detected at 48 kDa.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His404 of human MAP4K3 protein.
Background	The mTORC1 kinase complex is a critical regulator of cell growth (1,2). Its activity is modulated by growth factors and nutrients including amino acids (1,2). MAP4K3 is a mediator between nutrient signal and mTORC1 (1). Research studies suggest that amino acid sufficiency leads to the phosphorylation of Ser170 on MAP4K3, which activates mTORC1 (3).

Specifications