NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Millipore Active, N-Terminal 6his-Tagged, Recombinant, Cam Kinase Iiγ, Amino Acids 1-330, For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
Active, N-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330, for use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
expressed by baculovirus in Sf21 cells
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_172172.1
NM_001222.2
NM_172169.1
NM_172170.2
NM_172171.1
NM_172173.1
Entrez Gene Summary
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined.
Gene Symbol
CAMK2G
MGC26678
CAMKG
CAMK-II
CAMK
FLJ16043
Protein Target
CaMKIIγ
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
CAMK
UniProt Number
Q13555
UniProt Summary
FUNCTION: SwissProt: Q13555 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. SIZE: 558 amino acids; 62609 Da SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. SIMILARITY: SwissProt: Q13555 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
Molecular Weight
41.2kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545)
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
