PL-SAX for Prep to Process

PL-SAX strong anion-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.;The strong anion-exchange functionalities, covalently linked to a chemically stable polymer, facilitate anion-exchange purifications over a wider pH range. This stability can be exploited for column sanitation and clean-up, and also enables the use of denaturing conditions and stabilizing/solubilizing agents, as encountered in the purification of synthetic oligonucleotides with self-complementary sequences.