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Sigma-Aldrich 1-Deoxynojirimycin
List Price $777.40 Your Price $777.40
Sigma-Aldrich 1-Deoxynojirimycin - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-08012-10MG
MFG.PART: 08012-10MG
UNSPSC: 41116107
Manufacturer: Sigma-Aldrich
grade
analytical standard
Quality Level
100
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
format
neat
SMILES string
OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H13NO4/C8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key
LXBIFEVIBLOUGU-JGWLITMVSA-N
Related Categories
Phytochemical Standards
General description
1-Deoxynojirimycin is a polyhydroxypiperidine alkaloid and glucose analog, that has an -NH group substituting the O atom in the pyranose ring. It shows a significant α-glucosidase inhibitory effect in addition to antioxidant, antimicrobial, antidiabetic, antitumor, and anti-inflammatory behavior. It is commonly found in the roots of mulberry trees.[1]
[1]
[1]
Application
DNJ may be used as a reference standard for the determination of DNJ in:
- Mulberry leaves by high-performance liquid chromatography (HPLC) equipped with evaporative light scattering detector (ELSD)[2] as well as direct analysis in real-time (DART) ionization source coupled with triple quadrupole tandem mass spectrometry (MS/MS).[3]
- Silkworms by hydrophilic interaction chromatography (HILIC) with MS/MS operating on multiple reaction monitoring (MRM) mode.[4]
- Mulberry leaves of 132 varieties belonging to nine Morus species following its derivatization with fluorenylmethyl chloroformate (FMOC-Cl) by high-performance liquid chromatography (HPLC) combined with photodiode array (PDA) detector
- Development of an analytical method based on hydrophilic interaction chromatography (HILIC) coupled with tandem mass spectrometry (MS/MS) in positive ion electrospray ionization mode in the leaves of 32 cultivars of different Morus species
- HPLC method-based separation and quantification in the ethanol extracts of the leaves of Morus alba L. and Morus nigra with fluorimetric detection following pre-column derivatization with 9-fluorenylmethyl chloroformate
- 146 varieties of mulberry fruits from nine genera by HPLC in combination with UV-Vis dual-wavelength detection
- Human plasma by hybrid quadrupole/linear ion trap tandem mass spectrometry (QTRAP MS/MS).[5]
wgk_germany
WGK 1
| SKU | SIAL-08012-10MG |
|---|---|
| Supplier Part Number | 08012-10MG |
| UM | EA |
| UNSPSC | 41116107 |
| Manufacturer | Sigma-Aldrich |
| Temperature | room temp |
| Refrigerated-Frozen | N |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | N |
| CAS Number | 19130-96-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |