17(Allylamino)-17-demethoxygeldanamycin
75747-14-7
585.7
C31H43N3O8
DMSO, Methanol
-20°C
17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognized for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecuLar chaperone involved in protein folding and stabilization.
It is often used as a tool to study Hsp90-dependent processes. By inhibiting Hsp90, 17-AAG impacts the stability and function of various client proteins, many of which are involved in critical celluLar processes, including signal transduction and cell cycle reguLation. Similar to geldanamycin, 17-AAG is particuLarly relevant in cancer research, as Hsp90 is often crucial for the stability of oncoproteins.
Researchers use 17-AAG to explore the molecuLar mechanisms of Hsp90 inhibition, with potential applications in understanding cancer biology and developing therapeutic strategies.
0 lbs
1.25 x 1.75 x 1.25
Research or further manufacturing use only, not for food or drug use.