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AG Scientific g-418 Sulfate, 5X1 g
List Price $143.83 Your Price $143.83
AG Scientific g-418 Sulfate (5 X 1G) aminoglycoside ATB that causes a chain of nonsense mutations during translation.G418 binds to the 80S subunit of the ribosome by blocking the elongation phase of PRT - AG (Additional S&H or Hazmat Fees May Apply)
NETA PART: RPI-G-1033-5X1G
MFG.PART: G-1033-5X1G
UNSPSC: 51102800
Manufacturer: AG Scientific
AG Scientific
(Additional S&H Or Hazmat Fees May Apply) - AG
Description:
g-418 Sulfate is an aminoglycoside antibiotic that is synthesized from Micromonospora rhodorangea and functions by causing a chain of nonsense mutations during translation.
Due to translation g-418 inhibited polypeptide synthesis and protein elongation. g-418 binds to the 80S subunit of the ribosome by blocking the elongation phase of protein synthesis, both in prokaryotic and eukaryotic cells. It also shows activity against protozoa, cecal amoebiasis, and helminthes.
Applications:
- Used routinely in molecular genetics experiments for selecting eukaryotic transformants
- Used in plant and mammalian cell culture as a selectable marker
- Used as a gene selection antibiotic that has a powerful new role in genome editing, utilizing the CRISPR/CAS9 system.
- Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro
(Additional S&H Or Hazmat Fees May Apply) - AG
| SKU | RPI-G-1033-5X1G |
|---|---|
| Supplier Part Number | G-1033-5X1G |
| UM | PK |
| UNSPSC | 51102800 |
| Manufacturer | AG Scientific |
| MSDS URL | Click here |
| Temperature | 4°C |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Japan |
| ProductLine | AG |
| Qty | 5 |
| MinOrderQty | 1 |
| Width | 15 |
| Depth | 15 |
| Height | 15 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 108321-42-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |