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Cayman Leukotriene D4-d5
List Price $321.00 Your Price $321.00
Cayman Leukotriene D4-d5 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10006199-25
MFG.PART: 10006199-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Leukotriene D4-d5 (LTD4-d5) is intended for use as an internal standard for the quantification of LTD4 (Item No. 20310) by GC- or LC-MS. LTD4 is an active metabolite of LTC4 (Item No. 20210) and a constituent of slow-reacting substance of anaphylaxis (SRS-A).1,2 It is formed via metabolism of LTC4 by γ-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals.3 In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal.4 It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
S-[(1R,2E,4E,
CAS Number
1240398-17-7
Synonyms
- LTD4-
d5
Molecular Formula
C25H35D5N2O6S
Formula Weight
501.7
Purity
≥99% deuterated forms (d1-
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/mL
- DMSO: 50 mg/mL
- Ethanol: 1 mg/mL
- PBS (pH 7.2): .1 mg/mL
λmax
280 nm
SMILES
N[C@H](C(NCC(O)=O)=O)CS[C@@H]([C@@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]
InChi Code
InChI=1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20-,21-,22+/m0/s1/i1D3,2D2
InChi Key
YEESKJGWJFYOOK-HXHZKDJLSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-10006199-25 |
|---|---|
| Supplier Part Number | 10006199-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1240398-17-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |