Cayman Oleyl Anilide

Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC₅₀ = 26 µM).¹ It induces splenomegaly in C57BL/6 mice and leads to weakness, weight loss, cachexia, and death in A/J mice with increases in serum IgG and IgM levels in both strains.² Oleyl anilide has been found in aniline-denatured rapeseed cooking oil, which has been associated with toxic oil syndrome, a chemically induced autoimmune syndrome characterized by acute pulmonary inflammation and eosinophilia, severe myalgia, and chronic peripheral neuropathy.^3,4,5

WARNING This product is not for human or veterinary use.