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Cayman Zileuton
List Price $173.00 Your Price $173.00
Cayman Zileuton - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10006967-50
MFG.PART: 10006967-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor.1 It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4; Item No. 20110) production induced by the calcium ionophore A23187 (Item No. 11016) in purified human peripheral blood polymorphonuclear leukocytes (PMNLs; IC50 = 0.6 µM). Zileuton (10 mg/kg, p.o.) prevents antigen challenge-induced increases in specific lung resistance in a sheep model of asthma at 4 to 8 hours post-challenge following administration 2 hours pre-challenge.2 Formulations containing zileuton have been used in the prophylaxis and chronic treatment of asthma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-
CAS Number
111406-87-2
Synonyms
- A 64077
Molecular Formula
C11H12N2O2S
Formula Weight
236.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2)(1:1): .5 mg/mL
- Ethanol: 10 mg/mL
λmax
203, 230, 260, 299 nm
SMILES
CC(N(C(N)=O)O)C(S1)=CC2=C1C=CC=C2
InChi Code
InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
InChi Key
MWLSOWXNZPKENC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10006967-50 |
|---|---|
| Supplier Part Number | 10006967-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 111406-87-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |