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Cayman (+)-WIN 55,212-2 (mesylate)
List Price $488.00 Your Price $488.00
Cayman (+)-WIN 55,212-2 (mesylate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10009023-50
MFG.PART: 10009023-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
(+)-WIN 55,212-2 (mesylate) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.1 In primary cultures of rat cerebral cortex neurons, (+)-WIN 55,212-2 (mesylate) (0.01-100 nM) increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve.2 This effect is fully counteracted by rimonabant (Item No. 9000484) at a concentration of 10 nM, by decreasing Ca2+ concentrations below 0.2 mm, or by the IP3 receptor antagonist xestospongin C (Item No. 64950) at a concentration of 1 µM. (+)-WIN 55,212-2 (mesylate) induces release of the proinflammatory neuropeptide CGRP from trigeminal ganglion (TG) neurons in a calcium-dependent manner with an EC50 value of 26 µM.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[(3R)-2,3-
CAS Number
131543-23-2
Molecular Formula
C27H26N2O3 • CH3SO3H
Formula Weight
522.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
λmax
219, 246, 330 nm
SMILES
O=C(C1=CC=CC2=C1C=CC=C2)C3=C(C)N(C4=C3C=CC=C4OC5)[C@@H]5CN6CCOCC6.CS(=O)(O)=O
InChi Code
InChI=1S/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m1./s1
InChi Key
FSGCSTPOPBJYSX-VEIFNGETSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10009023-50 |
|---|---|
| Supplier Part Number | 10009023-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 131543-23-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |