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Cayman CAY10578
List Price $20.00 Your Price $20.00
Cayman CAY10578 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10011264-1
MFG.PART: 10011264-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, Cdk5, and MSK1).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4,5,6,7-
CAS Number
19231-60-8
Molecular Formula
C10H3I4NO4
Formula Weight
708.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/mL
- DMF:PBS (pH 7.2) 1:5: 0.15 mg/mL
- DMSO: 5 mg/mL
λmax
263 nm
SMILES
OC(=O)CN1C(=O)c2c(C1=O)c(I)c(I)c(I)c2I
InChi Code
InChI=1S/C10H3I4NO4/c11-5-3-4(6(12)8(14)7(5)13)10(19)15(9(3)18)1-2(16)17/h1H2,(H,16,17)
InChi Key
FLSXICNYHDJIAW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10011264-1 |
|---|---|
| Supplier Part Number | 10011264-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United Kingdom |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 19231-60-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |