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Cayman Clioquinol
List Price $42.00 Your Price $42.00
Cayman Clioquinol - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10021-10
MFG.PART: 10021-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Clioquinol is a metal-chelating antimicrobial agent with neuroprotective properties.,, It inhibits the growth of A. fumigatus with MIC values of 1, >32, 8, and 16 µg/mL in media containing no metal, iron, zinc, and copper, respectively. Clioquinol (37 mg/kg) decreases neuronal loss in the substantia nigra pars compacta (SNc) and increases time spent in the novel arm of a Y-maze in the α-synuclein hA53T transgenic mouse model of Parkinsons disease. It reduces brain atrophy and iron content, increases nigral tyrosine hydroxylase phosphorylation, and rescues behavioral impairments in the rotarod and Y-maze tests in tau knockout mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-chloro-7-
CAS Number
130-26-7
Synonyms
- Iodochlorohydroxyquin
- NSC 3531
- NSC 74938
Molecular Formula
C9H5ClINO
Formula Weight
305.5
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:8): 0.5 mg/mL
λmax
255, 324 nm
SMILES
OC1=C2C(C=CC=N2)=C(Cl)C=C1I
InChi Code
InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChi Key
QCDFBFJGMNKBDO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10021-10 |
|---|---|
| Supplier Part Number | 10021-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 130-26-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |