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Cayman F16
List Price
$423.00
Your Price
$423.00
Cayman F16 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-10022-50
MFG.PART:
10022-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function.1 F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a potential antitumor agent, F16 is an easily visualized fluorescent molecule which can also be used to visualize mitochondria under confocal microscopy. The mechanism of apoptosis induction by F16 is believed to be through disruption of the mitochondrial transmembrane potential.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(1E)-2-(1H-
CAS Number
36098-33-6
Molecular Formula
C16H15N2 • I
Formula Weight
362.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 25 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 500 µg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
443 nm
SMILES
[H]N1C=C(/C=C/C2=CC=[N+](C)C=C2)C3=CC=CC=C31.[I-]
InChi Code
InChI=1S/C16H14N2.HI/c1-18-10-8-13(9-11-18)6-7-14-12-17-16-5-3-2-4-15(14)16;/h2-12H,1H3;1H
InChi Key
UURAKYSOOXPORG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10022-50 |
|---|---|
| Supplier Part Number | 10022-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 36098-33-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |