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Cayman TMS
List Price
$516.00
Your Price
$516.00
Cayman TMS - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-10038-50
MFG.PART:
10038-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids; eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.1 It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making it a useful tool to differentiate between various CYP450 families.1 In cultured human colon cancer cells, TMS induces apoptosis and inhibits cell growth with an IC50 of 0.8 µg/mL.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(1E)-2-
CAS Number
24144-92-1
Synonyms
- 2,3,4,5-Tetramethoxystilbene
Molecular Formula
C18H20O4
Formula Weight
300.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS (pH 7.2) (1:1): 500 µg/mL
- DMSO: 20 mg/mL
- Ethanol: 400 µg/mL
λmax
219, 302, 326 nm
SMILES
COC1=CC(/C=C/C2=C(OC)C=C(OC)C=C2)=CC(OC)=C1
InChi Code
InChI=1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+
InChi Key
JDBCWSHYEQUBLW-AATRIKPKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10038-50 |
|---|---|
| Supplier Part Number | 10038-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 24144-92-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |