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Cayman 6(S)-Lipoxin A4
List Price $659.00 Your Price $659.00
Cayman 6(S)-Lipoxin A4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10049-50
MFG.PART: 10049-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Item No. 90410). It is formed from arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4) intermediate, or by 15-LO followed by 5-LO, with 15(S)-HETE (Item No. 34720) and 5(S)-Hp-15(S)-HETE intermediates.1 The generation of 6(S)-LXA4 and LXA4 typically requires transcellular metabolism of arachidonic acid.1,2 For example, LTA4 synthesized in neutrophils by 5-LO is metabolized to LXA4 in platelets by 12-LO.1 6(S)-LXA4 has been detected in co-incubations of human polymorphonuclear leukocytes (PMNs) and platelets.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S,6S,15S-
CAS Number
94292-80-5
Synonyms
- 5(S),6(S)-Lipoxin A4
- 6-epi-Lipoxin A4
- 6(S)-LXA4
- 5(S),6(S),15(S)-TriHETE
Molecular Formula
C20H32O5
Formula Weight
352.5
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/mL
- Ethanol: 50 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
302 nm
SMILES
CCCCCCC(O)\C=C\C=C/C=C\C=C/C(O)C(O)CCCC(=O)O
InChi Code
InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18-,19-/m0/s1
InChi Key
IXAQOQZEOGMIQS-UZDWIPAXSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-10049-50 |
|---|---|
| Supplier Part Number | 10049-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 94292-80-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |