Cayman Monoacylglycerol Lipase (FL) Polyclonal Antibody

Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase to mobilize fatty acids from the triglyceride stores of adipocytes.^, MAGL has a molecular weight of ~33 kDa and exhibits a high degree of homology among human, murine, and rat at the amino acid level.^,,, The enzyme is expressed in a variety of tissues with most abundant expression in skeletal muscle and adipose tissue, suggesting a role of MAGL in monoglyceride hydrolysis in diverse tissues. Cayman’s MAGL (FL) Polyclonal Antibody can be used for Western blot, immunocytochemistry, and immunohistochemistry analysis for MAGL.

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