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Cayman Capecitabine
List Price $98.00 Your Price $98.00
Cayman Capecitabine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10487-1
MFG.PART: 10487-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Capecitabine is a prodrug of 5-fluorouracil (5-FU; Item No. ). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC50s = 97, 578, and 994 µM, respectively) and is inactive in a variety of cancer cell lines, including COLO205, HCT116, and MCF-7 cells (IC50s = >1,000 µM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-
CAS Number
154361-50-9
Synonyms
- Ro 09-
1978
Molecular Formula
C15H22FN3O6
Formula Weight
359.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 14 mg/mL
- DMSO: 12.5 mg/mL
- Ethanol: 5 mg/mL
- PBS (pH 7.2): 0.15 mg/mL
λmax
215, 243, 308 nm
SMILES
O=C1N([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)C=C(F)C(NC(OCCCCC)=O)=N1
InChi Code
InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
InChi Key
GAGWJHPBXLXJQN-UORFTKCHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10487-1 |
|---|---|
| Supplier Part Number | 10487-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 154361-50-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |