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Cayman AS-1269574
List Price $129.00 Your Price $129.00
Cayman AS-1269574 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10626-10
MFG.PART: 10626-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
GPR119, a glucose-dependent insulinotropic receptor, is a Gs protein-coupled receptor that is expressed in pancreas β-cells and intestinal L-cells.1 Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine and oleoyl ethanolamide increases intracellular cAMP levels and promotes glucose-stimulated insulin secretion.1,2 AS-1269574 is an agonist of GPR119 that is effective both in isolated cells and in vivo.3 It increases cAMP levels in HEK293 cells transfected with human GPR119 (EC50 = 2.5 μM) and glucose-stimulated insulin secretion in mice (100 mg/kg).3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[2-(4-
CAS Number
330981-72-1
Molecular Formula
C13H14BrN3O
Formula Weight
308.2
Purity
≥98%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMF:PBS (pH 7) (1:10): 0.1 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
λmax
253 nm
SMILES
BrC(C=C1)=CC=C1C2=NC(NCCO)=CC(C)=N2
InChi Code
InChI=1S/C13H14BrN3O/c1-9-8-12(15-6-7-18)17-13(16-9)10-2-4-11(14)5-3-10/h2-5,8,18H,6-7H2,1H3,(H,15,16,17)
InChi Key
DUKPGOOUJNUIOI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-10626-10 |
|---|---|
| Supplier Part Number | 10626-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 330981-72-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |