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Cayman CCG-50014
List Price $30.00 Your Price $30.00
Cayman CCG-50014 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-10802-1
MFG.PART: 10802-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
CCG-50014 is an inhibitor of regulator of g protein signaling 4 (RGS4) (IC50 = 30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. RGS proteins bind to the Gα subunits of activated heterotrimeric g proteins and accelerate the rate of GTP hydrolysis, acting as GTPase-activating proteins. CCG-50014 irreversibly binds and destabilizes RGS4 with no effect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(4-fluoro
CAS Number
883050-24-6
Molecular Formula
C16H13FN2O2S
Formula Weight
316.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 1 mg/mL
λmax
251 nm
SMILES
CC1=CC=C(N2SC(N(CC3=CC=C(F)C=C3)C2=O)=O)C=C1
InChi Code
InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3
InChi Key
QUIIIYITNGOFEI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-10802-1 |
|---|---|
| Supplier Part Number | 10802-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 883050-24-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |