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Cayman Epothilone B
List Price
$120.00
Your Price
$120.00
Cayman Epothilone B - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-10924-1
MFG.PART:
10924-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Epothilone B (Epo B) is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis., It induces mitotic arrest at the g2-M transition in Hs578T and HeLa cells (IC50 = 3 and 32 nM, respectively) as well as in multidrug resistant KB3-1 and KBV-
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7S,11S- dihydroxy- 8,8,10R,12S, 16R-penta methyl-3S- [(1E)-1S- methyl-2-(2- methyl-4- thiazolyl) ethenyl]-4,17- dioxabicyclo [14.1.0] heptadecane- 5,9-dione
CAS Number
152044-54-7
Synonyms
- Epo B
Molecular Formula
C27H41NO6S
Formula Weight
507.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
λmax
212, 250 nm
SMILES
CC1=NC(/C=C(C)/[C@@H](OC(C[C@H](O)C2(C)C)=O)C[C@@H]3O[C@]3(C)CCC[C@@](C)([H])[C@H](O)[C@@H](C)C2=O)=CS1
InChi Code
InChI=1S/C27H41NO6S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)33-23(30)13-21(29)26(5,6)25(32)17(3)24(15)31/h11,14-15,17,20-22,24,29,31H,8-10,12-13H2,1-7H3/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
InChi Key
QXRSDHAAWVKZLJ-PVYNADRNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10924-1 |
|---|---|
| Supplier Part Number | 10924-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 152044-54-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |