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Cayman A23187
List Price $269.00 Your Price $269.00
Cayman A23187 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11016-25
MFG.PART: 11016-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
A23187 is a calcium ionophore and a microbial metabolite that has been found in S. chartreusensis.1,2 It induces calcium overload and mitochondrial apoptosis in HEK293 cells when used at a concentration of 5 µM.1 A23187 (5 µM) induces the production of reactive oxygen species (ROS) and neutrophil extracellular trap (NET) formation in primary human neutrophils in a myeloperoxidase-, neutrophil elastase-, and citrullination-independent manner.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-(methyl
CAS Number
52665-69-7
Synonyms
- Calcimycin
Molecular Formula
C29H37N3O6
Formula Weight
523.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 1 mg/mL
λmax
226, 279, 379 nm
SMILES
O=C([C@@H](C)[C@]1([H])[C@H](C)C[C@@H](C)[C@@]2(O[C@H](CC3=NC(C(C(O)=O)=C(NC)C=C4)=C4O3)[C@H](C)CC2)O1)C5=CC=CN5
InChi Code
InChI=1S/C29H37N3O6/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35)/t15-,16-,17-,18-,22-,27+,29+/m1/s1
InChi Key
HIYAVKIYRIFSCZ-CYEMHPAKSA-N
Origin
Bacterium/Streptomyces chartreusis
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11016-25 |
|---|---|
| Supplier Part Number | 11016-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Israel |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 52665-69-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |