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Cayman CAY10665
List Price $98.00 Your Price $98.00
Cayman CAY10665 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11044-50
MFG.PART: 11044-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA).1 In this model, the ω-3 PUFA eicosapentaenoic acid (EPA, 3-10 μM) reduces the contraction rate of cells, indicating a positive antiarrhythmic effect.1 Cytochrome P450 metabolites of EPA are more potent, with 17,18-epoxyeicosatetraenoic acid (17,18-EET) reducing contractions at 30 nM.2 CAY10665 is a bioisostere of 17,18-EET which is approximately 50% more effective at reducing arrhythmic contraction frequency, without affecting amplitude, when tested at 30 nM.3 This disubstituted oxamide represents a stable analog of 17,18-EET which may be used to study the mechanism of regulation of cardiomyocyte contractility by EPA metabolites.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
16-[[2-
CAS Number
1235543-17-5
Molecular Formula
C19H34N2O4
Formula Weight
354.5
Purity
≥98%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
SMILES
O=C(C(NC)=O)NCCCC/C=C\CCCCCCCCCC(O)=O
InChi Code
InChI=1S/C19H34N2O4/c1-20-18(24)19(25)21-16-14-12-10-8-6-4-2-3-5-7-9-11-13-15-17(22)23/h6,8H,2-5,7,9-16H2,1H3,(H,20,24)(H,21,25)(H,22,23)/b8-6-
InChi Key
WKESFWWKRDQART-VURMDHGXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-11044-50 |
|---|---|
| Supplier Part Number | 11044-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1235543-17-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |