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Cayman Nifedipine
List Price $42.00 Your Price $42.00
Cayman Nifedipine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11106-5
MFG.PART: 11106-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 μM.1 Nifedipine (1 μM) reduces TGF-β-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse model of pulmonary fibrosis induced by bleomycin (Item No. 13877) when administered at a dose of 10 mg/kg per day.2 It also reduces increases in mean arterial blood pressure induced by angiotensin II (Item No. 17150) in spontaneously hypertensive rats when administered at a dose of 10 μg/kg.3 Formulations containing nifedipine have been used in the treatment of hypertension and angina.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,4-
CAS Number
21829-25-4
Synonyms
- BAY 1040
Molecular Formula
C17H18N2O6
Formula Weight
346.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL
- Ethanol: 1 mg/mL
λmax
236, 334, 360 nm
SMILES
CC1=C(C(OC)=O)C(C(C(OC)=O)=C(C)N1)C2=CC=CC=C2[N+]([O-])=O
InChi Code
InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChi Key
HYIMSNHJOBLJNT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11106-5 |
|---|---|
| Supplier Part Number | 11106-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 21829-25-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |