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Cayman Alternariol monomethyl ether
List Price $124.00 Your Price $124.00
Cayman Alternariol monomethyl ether - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11307-1
MFG.PART: 11307-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Alternariol monomethyl ether (AME) is a mycotoxin originally isolated from A. brassicae extracts. AME is a common contaminant in cereal grains such as wheat, barley, and sorghum that is cytotoxic to bacterial (MIC = 500 μg/disc for B. mycoides in a bacterial halo assay) and mammalian cells (IC50 = 120 μM in HCT116 cells)., It inhibits human topoisomerase II and bacterial gyrase at initial inhibitory concentrations of 25 and 10 μM, respectively. AME selectively inhibits monoamine oxidase A (MOA-A; Ki = 0.34 μM)., AME also provokes DNA damage that induces mitochondrial permeability transition pore-mediated activation of apoptosis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,7-dihydroxy-
CAS Number
23452-05-3
Synonyms
- AME
- NSC 638262
Molecular Formula
C15H12O5
Formula Weight
272.3
Purity
≥98%
Formulation
A solid
Solubility
- Dichloromethane: soluble
- Methanol: soluble
SMILES
CC1=C(C2=C(C(O3)=O)C(O)=CC(OC)=C2)C3=CC(O)=C1
InChi Code
InChI=1S/C15H12O5/c1-7-3-8(16)4-12-13(7)10-5-9(19-2)6-11(17)14(10)15(18)20-12/h3-6,16-17H,1-2H3
InChi Key
LCSDQFNUYFTXMT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11307-1 |
|---|---|
| Supplier Part Number | 11307-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Switzerland |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 23452-05-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |