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Cayman Oligomycin A
List Price $62.00 Your Price $62.00
Cayman Oligomycin A - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11342-1
MFG.PART: 11342-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis in a variety of cell types (average GI50 = 270 nM).,, Oligomycin A exhibits antifungal, antitumor, and nematocidal activities, but has poor solubility in water and other biocompatible solvents, which limits its clinical application.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(1S,2R,4E,5R,6R,6S,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,28R,29S)-
CAS Number
579-13-5
Synonyms
- MCH 32
Molecular Formula
C45H74O11
Formula Weight
791.1
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
λmax
225 nm
SMILES
O=C([C@H](C)[C@@H](O)[C@H](C)/C=C/1)[C@@H](C)[C@H](O)[C@@H](C)C([C@](O)(C)[C@H](O)[C@@H](C)C/C=C/C=C/[C@](CC)([H])CC[C@]2([H])[C@H](C)[C@]([C@@H](C)[C@]3(CC[C@@H](C)[C@](C[C@@H](O)C)([H])O3)O2)([H])OC1=O)=O
InChi Code
InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-
InChi Key
MNULEGDCPYONBU-WMBHJXFZSA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11342-1 |
|---|---|
| Supplier Part Number | 11342-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 579-13-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |