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Cayman Docetaxel (hydrate)
List Price $372.00 Your Price $372.00
Cayman Docetaxel (hydrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11637-50
MFG.PART: 11637-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel (Item No. 10461).1 It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 µM and is cytotoxic to J774.2 cells (EC50 = 0.05 µM).2 In vivo, docetaxel inhibits tumor growth in several cancer models, including B16 murine melanoma and P388 murine leukemia models.1 Formulations containing docetaxel have been used in the treatment of head and neck, breast, and non-small cell lung cancer, gastric adenocarcinoma, and castration-resistant prostate cancer.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(αR,βS)-β-
CAS Number
700367-34-6
Synonyms
- DTX
- NSC 628503
- RP 56976
- Taxotel
Molecular Formula
C43H53NO14 • XH2O
Formula Weight
807.9
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL
- Ethanol: 1.5 mg/mL
λmax
229 nm
SMILES
CC(C1=C(C)[C@@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C2=CC=CC=C2)=O)C3)(C)[C@]3(O)[C@@H](OC(C4=CC=CC=C4)=O)[C@@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@@H]6O)([H])[C@]6(C)C([C@@H]1O)=O.O
InChi Code
InChI=1S/C43H53NO14.H2O/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45;/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52);1H2/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+;/m0./s1
InChi Key
YWKYKORYUFJSCV-XKIQGVRMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11637-50 |
|---|---|
| Supplier Part Number | 11637-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 700367-34-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |