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Cayman 12-Deoxywithastramonolide
List Price $224.00 Your Price $224.00
Cayman 12-Deoxywithastramonolide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11669-1
MFG.PART: 11669-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
12-Deoxywithastramonolide is a withanolide found in W. somnifera roots. It has anti-inflammatory activity, reducing Tnf-α and increasing Il-10 production in mice following oral administration at doses ranging from 50-200 mg/kg. 12-Deoxywithastramonolide also reduces the growth of A549 lung and HT-29 colorectal cancer cells (IC50s = 47.1 and 29.8 μM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6α,7α-epoxy-
CAS Number
60124-17-6
Synonyms
- Baimantuoluoside C aglycone
- 27-Hydroxywithanolide B
Molecular Formula
C28H38O6
Formula Weight
470.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/mL
- DMSO: 0.1 mg/mL
- Ethanol: 20 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
λmax
224 nm
SMILES
CC(C1)=C(CO)C(O[C@@]1([H])[C@@H](C)[C@@]2([H])CC[C@@]3([H])[C@]4([H])[C@H]5[C@H](O5)[C@@]([C@@]6(C)[C@@]4([H])CC[C@@]32C)(O)CC=CC6=O)=O
InChi Code
InChI=1S/C28H38O6/c1-14-12-20(33-25(31)16(14)13-29)15(2)17-7-8-18-22-19(9-11-26(17,18)3)27(4)21(30)6-5-10-28(27,32)24-23(22)34-24/h5-6,15,17-20,22-24,29,32H,7-13H2,1-4H3/t15-,17+,18-,19-,20+,22-,23-,24-,26+,27-,28-/m0/s1
InChi Key
AWVMHXZWAKRDGG-MEBIVHGNSA-N
Origin
Plant/Withania somnifera
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-11669-1 |
|---|---|
| Supplier Part Number | 11669-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 60124-17-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |