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Cayman Catharanthine (tartrate)
List Price $363.00 Your Price $363.00
Cayman Catharanthine (tartrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11695-500
MFG.PART: 11695-500
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Catharanthine is an indole alkaloid that has been found in C. roseus and has diverse biological activities.1,2,3,4,5 It is a precursor in the biosynthesis of the antimitotic agents vinblastine (Item No. 11762) and vincristine (Item No. 11764).1 Catharanthine (320 µM) inhibits microtubule assembly and the proliferation of HCT116 colon cancer cells (IC50 = 60 µg/mL).2,3 It induces the release of amylase from mouse pancreas preparations when used at a concentration of 100 µM.4 Catharanthine (0.5-20 mg/kg) decreases blood pressure and heart rate in anesthetized normotensive rats.5
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2α,5β,6α)-
CAS Number
4168-17-6
Synonyms
- (+)-
3,4- Didehydrocoronaridine
Molecular Formula
C21H24N2O2 • 1/2C4H6O6
Formula Weight
486.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
λmax
224, 283 nm
SMILES
CCC1=C[C@H]2C[C@]([C@]1([H])[N@@](C2)CC3)(C(OC)=O)C4=C3C5=C(N4)C=CC=C5.OC([C@@H]([C@@H](O)C(O)=O)O)=O.CCC6=C[C@H]7C[C@]([C@]6([H])[N@@](C7)CC8)(C(OC)=O)C9=C8C%10=C(N9)C=CC=C%10
InChi Code
InChI=1S/2C21H24N2O2.C4H6O6/c2*1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18;5-1(3(7)8)2(6)4(9)10/h2*4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t2*13-,19+,21-;1-,2-/m001/s1
InChi Key
OXIDCVCPXUNSCI-DWGLLIDUSA-N
Origin
Plant/Vinca rosea
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11695-500 |
|---|---|
| Supplier Part Number | 11695-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Switzerland |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 4168-17-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |