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Cayman Diacerein
List Price $93.00 Your Price $93.00
Cayman Diacerein - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11710-50
MFG.PART: 11710-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Diacerein is a prodrug form of the anthraquinone derivative rhein (Item No. 17345).1 It inhibits RANKL- and IL-1β-induced differentiation of RAW 264.7 cells into osteoclasts when used at a concentration of 20 µg/mL.2 Diacerein (20 µg/mL) reduces levels of interleukin-1β-converting enzyme (ICE), also known as caspase-1, as well as IL-1β, and IL-18 in the superficial zone of human osteoarthritic cartilage explants.3 It decreases carrageenan-, dextran-, or zymosan-induced paw edema in rats when administered at a dose of 100 mg/kg.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4,5-
CAS Number
13739-02-1
Synonyms
- DAR
- Diacerhein
- 4,5-
Diacetylrhein - SF 277
Molecular Formula
C19H12O8
Formula Weight
368.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: 15 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
λmax
216, 255, 337 nm
SMILES
OC(C(C=C1OC(C)=O)=CC2=C1C(C3=C(C2=O)C=CC=C3OC(C)=O)=O)=O
InChi Code
InChI=1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
InChi Key
TYNLGDBUJLVSMA-UHFFFAOYSA-N
Origin
Plant/Aloe barbadensis
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11710-50 |
|---|---|
| Supplier Part Number | 11710-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 13739-02-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |