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Cayman 6α-Methylprednisolone 21-hemisuccinate
List Price $28.00 Your Price $28.00
Cayman 6α-Methylprednisolone 21-hemisuccinate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-11800-10
MFG.PART: 11800-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
6α-Methylprednisolone 21-hemisuccinate is a prodrug form of the synthetic glucocorticoid methylprednisolone (Item No. ). It is converted to methylprednisolone by carboxylesterase 2 (CES2). Nanoliposomes containing 6α-methylprednisolone 21-hemisuccinate decreases disease severity in a rat model of adjuvant-induced arthritis. Formulations containing 6α-methylprednisolone 21-hemisuccinate have been used as anti-inflammatory agents and immunosuppressants with indications in allergic reactions and dermatologic, renal, gastrointestinal, respiratory, and ophthalmic diseases, as well as endocrine, hematologic, and rheumatic disorders.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
21-
CAS Number
2921-57-5
Synonyms
- Methylprednisolone 21-succinate
- MPS
Molecular Formula
C26H34O8
Formula Weight
474.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
λmax
243 nm
SMILES
O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC(O)=O)=O)=O)=C1
InChi Code
InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1
InChi Key
IMBXEJJVJRTNOW-XYMSELFBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11800-10 |
|---|---|
| Supplier Part Number | 11800-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2921-57-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |