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Cayman Madecassic Acid
List Price
$197.00
Your Price
$197.00
Cayman Madecassic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-11854-1
MFG.PART:
11854-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities.,, It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. ), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 µg/mL. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. ). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2α,3β,4α,6β)-
CAS Number
18449-41-7
Synonyms
- Brahmic Acid
- NSC 88135
Molecular Formula
C30H48O6
Formula Weight
504.7
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2) (1:9): 0.1 mg/mL
- DMSO: 5 mg/mL
- Ethanol: 3 mg/mL
SMILES
OC[C@]1(C)[C@@H](O)[C@H](O)C[C@@]2(C)[C@@]1([H])[C@H](O)C[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5
InChi Code
InChI=1S/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21-,22+,23-,24+,26-,27+,28-,29-,30?/m1/s1
InChi Key
PRAUVHZJPXOEIF-QUKJEOBDSA-N
Origin
Plant/Centella asiatica
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-11854-1 |
|---|---|
| Supplier Part Number | 11854-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 18449-41-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |